Vinay Prasad often writes about bias in research. In my field, I also see bias in research studies. I have always considered the research on Premarin biased. I don’t like the 60 years of Wyeth studies “demonstrating” that Premarin was good for the heart, vessels, breasts and brain. I know it was good for hot flushes, osteoporosis, bladders and vaginas. The Federal Drug Administration’s (FDA’s) endorsing the Wyeth studies for sixty years is reprehensible.